Protection from Lethal Apoptosis in Lipopolysaccharide-Induced Acute Lung Injury in Mice by a Caspase Inhibitor

LPS (lipopolysaccharide) is one of the major factors that induce acute lung injury. Recently, it was reported that LPS induced disseminated endothelial apoptosis, preceding nonendothelial tissue damage. Caspases play important roles in apoptosis, including tumor necrosis factor-α-induced apoptosis,...

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Hauptverfasser: Kawasaki, Masayuki, Kuwano, Kazuyoshi, Hagimoto, Naoki, Matsuba, Tokuji, Kunitake, Ritsuko, Tanaka, Takuo, Maeyama, Takashige, Hara, Nobuyuki
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Investigative Pathology 2000
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1850133/
https://ncbi.nlm.nih.gov/pubmed/10934162
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