Characterization of Genomic Alterations in Hepatoblastomas : A Role for Gains on Chromosomes 8q and 20 as Predictors of Poor Outcome

As data on the genomic alterations in hepatoblastoma (HB) are limited, 34 HB tumors and three HB cell lines were screened for DNA copy number changes by comparative genomic hybridization. The average number of chromosomal imbalances per tumor was 2.3 ± 0.5 (mean ± SEM) with gains sevenfold more freq...

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Asıl Yazarlar: Weber, Ruthild G., Pietsch, Torsten, von Schweinitz, Dietrich, Lichter, Peter
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Investigative Pathology 2000
Konular:
Regular Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC1850131/
https://ncbi.nlm.nih.gov/pubmed/10934159
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