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Osteoprotegerin Ligand Modulates Murine Osteoclast Survival in Vitro and in Vivo

Osteoprotegerin ligand (OPGL) targets osteoclast precursors and osteoclasts to enhance differentiation and activation, however, little is known about OPGL effects on osteoclast survival. In vitro, the combination of OPGL + colony-stimulating factor-1 (CSF-1) is required for optimal osteoclast surviv...

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Bibliografiska uppgifter
Huvudupphovsmän: Lacey, David L., Tan, Hong Lin, Lu, John, Kaufman, Steven, Van, Gwyneth, Qiu, Wanrang, Rattan, Alana, Scully, Sheila, Fletcher, Frederick, Juan, Todd, Kelley, Michael, Burgess, Teresa L., Boyle, William J., Polverino, Anthony J.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Investigative Pathology 2000
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC1850124/
https://ncbi.nlm.nih.gov/pubmed/10934148
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