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4′-Iodo-4′-Deoxydoxorubicin Disrupts the Fibrillar Structure of Transthyretin Amyloid

Transthyretin (TTR) is a tetrameric protein synthesized mainly by the liver and the choroid plexus, from where it is secreted into the plasma and the cerebrospinal fluid, respectively. Some forms of polyneuropathy, vitreopathy, and cardiomyopathy are caused by the deposition of normal and/or mutant...

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Xehetasun bibliografikoak
Egile Nagusiak: Palha, Joana Almeida, Ballinari, Dario, Amboldi, Nadia, Cardoso, Isabel, Fernandes, Rui, Bellotti, Vittorio, Merlini, Giampaolo, Saraiva, Maria João
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Investigative Pathology 2000
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC1850080/
https://ncbi.nlm.nih.gov/pubmed/10854215
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