Interaction of the anthracycline 4'-iodo-4'-deoxydoxorubicin with amyloid fibrils: inhibition of amyloidogenesis.

All types of amyloidosis are structurally characterized by the cross beta-pleated sheet conformation of the fibrils, irrespective of their biochemical composition. The clinical observation that the anthracycline 4'-iodo-4'-deoxy-doxorubicin (IDOX) can induce amyloid resorption in patients with immun...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Merlini, G, Ascari, E, Amboldi, N, Bellotti, V, Arbustini, E, Perfetti, V, Ferrari, M, Zorzoli, I, Marinone, M G, Garini, P
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1995
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC42338/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7708755/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.7.2959
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