APC Mutations in Sporadic Medulloblastomas

The cerebellar medulloblastoma (WHO Grade IV) is a highly malignant, invasive embryonal tumor with preferential manifestation in children. Several molecular alterations appear to be involved, including isochromosome 17q and the p53, PTCH, and β-catenin gene mutations. In this study, 46 sporadic medu...

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Main Authors: Huang, Huatao, Mahler-Araujo, Betania M., Sankila, Anna, Chimelli, Leila, Yonekawa, Yasuhiro, Kleihues, Paul, Ohgaki, Hiroko
格式: Artigo
語言:Inglês
出版: American Society for Investigative Pathology 2000
主題:
Short Communications
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1850060/
https://ncbi.nlm.nih.gov/pubmed/10666372
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