Macrophages and neutrophils are the targets for immune suppression by glucocorticoids in contact allergy

Glucocorticoids (GCs) are widely used in the treatment of allergic skin conditions despite having numerous side effects. Here we use Cre/loxP-engineered tissue- and cell-specific and function-selective GC receptor (GR) mutant mice to identify responsive cell types and molecular mechanisms underlying...

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Detalhes bibliográficos
Main Authors: Tuckermann, Jan P., Kleiman, Anna, Moriggl, Richard, Spanbroek, Rainer, Neumann, Anita, Illing, Anett, Clausen, Björn E., Stride, Brenda, Förster, Irmgard, Habenicht, Andreas J.R., Reichardt, Holger M., Tronche, François, Schmid, Wolfgang, Schütz, Günther
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2007
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1849982/
https://ncbi.nlm.nih.gov/pubmed/17446934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI28034
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