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Release Factors 2 from Escherichia coli and Thermus thermophilus: structural, spectroscopic and microcalorimetric studies

Prokaryotic class I release factors (RFs) respond to mRNA stop codons and terminate protein synthesis. They interact with the ribosomal decoding site and the peptidyl-transferase centre bridging these 75 Å distant ribosomal centres. For this an elongated RF conformation, with partially unfolded core...

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Detalhes bibliográficos
Main Authors: Zoldák, Gabriel, Redecke, Lars, Svergun, Dmitri I., Konarev, Peter V., Voertler, C. Stefan, Dobbek, Holger, Sedlák, Erik, Sprinzl, Mathias
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1849895/
https://ncbi.nlm.nih.gov/pubmed/17272297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkl696
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