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Transgenic mice carrying an imbalance in the native ratio of A to B forms of progesterone receptor exhibit developmental abnormalities in mammary glands

In this report we document the creation of transgenic mice in which the native ratio of A and B forms of progesterone receptor (PR) has been altered by the introduction of additional A form as transgene. We also show that in these mice there is an aberration in mammary development. In ovariectomized...

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Detalhes bibliográficos
Main Authors: Shyamala, G., Yang, X., Silberstein, G., Barcellos-Hoff, M. H., Dale, E.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 1998
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC18483/
https://ncbi.nlm.nih.gov/pubmed/9435255
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