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Dynamical signatures of cellular fluctuations and oscillator stability in peripheral circadian clocks

Cell-autonomous and self-sustained molecular oscillators drive circadian behavior and physiology in mammals. From rhythms recorded in cultured fibroblasts we identified the dominant cause for amplitude reduction as desynchronization of self-sustained oscillators. Here, we propose a general framework...

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Detalles Bibliográficos
Autores principales: Rougemont, Jacques, Naef, Felix
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 2007
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1847945/
https://ncbi.nlm.nih.gov/pubmed/17353935
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/msb4100130
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