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Susceptibility of bovid herpesvirus 1 to antiviral drugs: in vitro versus in vivo efficacy of (E)-5-(2-Bromovinyl)-2'-deoxyuridine.

The relative efficacies of a variety of antiviral drugs against bovid herpesvirus 1 was investigated. (E)-5-(2-Bromovinyl)-2'-deoxyuridine and trifluorothymidine were found to be inhibitory at doses of 0.01 micrograms/ml in in vitro yield reduction and plaque reduction assays. In contrast, acylovir...

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Bibliografiske detaljer
Udgivet i:Antimicrob Agents Chemother
Principais autores: Babiuk, L A, Acres, S D, Misra, V, Stockdale, P H, De Clercq, E
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 1983
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC184794/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6307134/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.23.5.715
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