Regulation of norrin receptor frizzled-4 by Wnt2 in colon-derived cells

BACKGROUND: Norrin is a potent Wnt pathway ligand. Aberrant activation of this signaling pathway can result in colon tumors but the role of norrin-based signaling in the genesis of colon cancer, and its relationship to activation of the pathway by traditional Wnt ligands, is not defined. RESULTS: Fr...

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Bibliographic Details
Main Authors: Planutis, Kestutis, Planutiene, Marina, Moyer, Mary Pat, Nguyen, Anthony V, Pérez, Cherlyn A, Holcombe, Randall F
Format: Artigo
Language:Inglês
Published: BioMed Central 2007
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1847812/
https://ncbi.nlm.nih.gov/pubmed/17386109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2121-8-12
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