Engineering proteinase K using machine learning and synthetic genes

BACKGROUND: Altering a protein's function by changing its sequence allows natural proteins to be converted into useful molecular tools. Current protein engineering methods are limited by a lack of high throughput physical or computational tests that can accurately predict protein activity under...

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Detalhes bibliográficos
Main Authors: Liao, Jun, Warmuth, Manfred K, Govindarajan, Sridhar, Ness, Jon E, Wang, Rebecca P, Gustafsson, Claes, Minshull, Jeremy
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2007
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1847811/
https://ncbi.nlm.nih.gov/pubmed/17386103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6750-7-16
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