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Protein transduction as a means of effective manipulation of Cdc42 activity in primary T cells

The Rho family GTPase Cdc42 is a critical regulator of cellular polarization from yeast to man. An analysis of its function in T cell activation is therefore of interest. This analysis poses two substantial challenges, similar to the analysis of many other critical T cell signaling intermediates. Fi...

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Autori principali: Tskvitaria-Fuller, Irina, Mistry, Neeta, Sun, Shining, Wülfing, Christoph
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2006
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1847777/
https://ncbi.nlm.nih.gov/pubmed/17188290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jim.2006.10.017
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