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Synthetic Lethal Interactions Involving Loss of the Yeast ERG24- the Sterol C-14 Reductase Gene.
ERG2 and ERG24 are yeast sterol biosynthetic genes and are targets of the morpholine antifungals. ERG2 and ERG24 encode the C-8 sterol isomerase and the C-14 reductase, respectively. ERG2 is considered a non-essential gene but the viability of ERG24 is dependent upon genetic background, type of medi...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2006
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1847747/ https://ncbi.nlm.nih.gov/pubmed/17393212 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11745-006-1001-4 |
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