Mechanisms of TSC-mediated Control of Synapse Assembly and Axon Guidance

Tuberous sclerosis complex is a dominant genetic disorder produced by mutations in either of two tumor suppressor genes, TSC1 and TSC2; it is characterized by hamartomatous tumors, and is associated with severe neurological and behavioral disturbances. Mutations in TSC1 or TSC2 deregulate a conserve...

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Detalhes bibliográficos
Main Authors: Knox, Sarah, Ge, Hong, Dimitroff, Brian D., Ren, Yi, Howe, Katie A., Arsham, Andrew M., Easterday, Mathew C., Neufeld, Thomas P., O'Connor, Michael B., Selleck, Scott B.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2007
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1847706/
https://ncbi.nlm.nih.gov/pubmed/17440611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0000375
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