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Impact of Forced Selection of tRNAs on HIV-1 Replication and Genome Stability Highlight Preferences for Selection of Certain tRNAs

Human immunodeficiency virus (HIV-1) exclusively selects tRNA(Lys,3) as the primer for initiation of reverse transcription. How and why HIV-1 selects the tRNA is unresolved. To address this issue, we have generated HIV-1 in which the PBS was changed to be complementary to alternative tRNAs. In this...

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Hlavní autoři: Ni, Na, Morrow, Casey D.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2006
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1847643/
https://ncbi.nlm.nih.gov/pubmed/17070952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virusres.2006.09.009
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