Preferences for the selection of unique tRNA primers revealed from analysis of HIV-1 replication in peripheral blood mononuclear cells

BACKGROUND: All human immunodeficiency virus (HIV-1) uses a host tRNA(Lys,3 )as the primer for reverse transcription. The tRNA(Lys,3 )is bound to a region on the HIV-1 genome, the primer-binding site (PBS), that is complementary to the 18 terminal nucleotides of tRNA(Lys,3). How HIV-1 selects the tR...

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Detalhes bibliográficos
Main Authors: Moore-Rigdon, Kenda L, Kosloff, Barry R, Kirkman, Richard L, Morrow, Casey D
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2005
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1084362/
https://ncbi.nlm.nih.gov/pubmed/15790410
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4690-2-21
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