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Multiple roles for MSH2 in the repair of a deletion mutation directed by modified single-stranded oligonucleotides

The mechanism by which modified single-stranded oligonucleotides (MSSOs) direct base changes in genes is not completely understood, but there is evidence that DNA damage, repair and cell cycle checkpoint proteins are involved in the targeted nucleotide exchange (TNE) process. We are interested in th...

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Hlavní autoři: Maguire, Katie Kennedy, Kmiec, Eric B.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2006
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1847641/
https://ncbi.nlm.nih.gov/pubmed/17113727
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.gene.2006.08.014
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