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Effect of ketoconazole on the fungicidal action of amphotericin B in Candida albicans.

Amphotericin B-susceptible Candida albicans became resistant to the drug after growth in the presence of ketoconazole. Chromatographic analysis of cellular sterols showed that the organisms became depleted of ergosterol in parallel with the development of amphotericin B resistance. The implications...

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Detalhes bibliográficos
Main Authors: Sud, I J, Feingold, D S
Formato: Artigo
Idioma:Inglês
Publicado em: 1983
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC184642/
https://ncbi.nlm.nih.gov/pubmed/6299182
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