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Effect of ketoconazole on the fungicidal action of amphotericin B in Candida albicans.

Amphotericin B-susceptible Candida albicans became resistant to the drug after growth in the presence of ketoconazole. Chromatographic analysis of cellular sterols showed that the organisms became depleted of ergosterol in parallel with the development of amphotericin B resistance. The implications...

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Pubblicato in:Antimicrob Agents Chemother
Autori principali: Sud, I J, Feingold, D S
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology (ASM) 1983
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC184642/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6299182/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.23.1.185
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