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Effect of methylprednisolone on entry of ampicillin and gentamicin into cerebrospinal fluid in experimental pneumococcal and Escherichia coli meningitis.

The influence of methylprednisolone on the passage of ampicillin and gentamicin into and activity within cerebrospinal fluid was examined in two models of experimental meningitis. Steroid pretreatment reduced the concentrations of these drugs in purulent cerebrospinal fluid of rabbits with experimen...

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Détails bibliographiques
Publié dans:Antimicrob Agents Chemother
Auteurs principaux: Scheld, W M, Brodeur, J P
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology (ASM) 1983
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC184626/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6338816/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.23.1.108
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