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Comparison Study of the Kinetics of Ceftizoxime Penetration into Extravascular Spaces with Known Surface Area/Volume Ratio In Vitro and In Vivo in Rabbits

The extravascular kinetics of ceftizoxime were studied both in an in vitro kinetic model and in an in vivo rabbit model. Visking tubing chambers were used in both models to provide extravascular spaces with large or small volumes and surface areas, but identical surface area/volume ratios. Four rabb...

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Udgivet i:Antimicrob Agents Chemother
Principais autores: Van Etta, Linda L., Fasching, Claudine E., Peterson, Lance R., Gerding, Dale N.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 1983
Fag:
Pharmacology
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC184615/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6299185/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.23.1.49
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