Cognitive changes and modified processing of amyloid precursor protein in the cortical and hippocampal system after cholinergic synapse loss and muscarinic receptor activation

A number of in vitro studies have shown that activation of muscarinic receptors by cholinergic agonists stimulates the nonamyloidogenic, α-secretase-processing pathway of amyloid precursor protein (APP). To determine whether increased cholinergic neurotransmission can modify the APP processing in vi...

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Bibliografske podrobnosti

izdano v:	Proc Natl Acad Sci U S A
Principais autores:	Lin, L., Georgievska, B., Mattsson, A., Isacson, O.
Format:	Artigo
Jezik:	Inglês
Izdano:	National Academy of Sciences 1999
Teme:	Biological Sciences
Online dostop:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC18420/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10518584/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.21.12108
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