Cognitive changes and modified processing of amyloid precursor protein in the cortical and hippocampal system after cholinergic synapse loss and muscarinic receptor activation

A number of in vitro studies have shown that activation of muscarinic receptors by cholinergic agonists stimulates the nonamyloidogenic, α-secretase-processing pathway of amyloid precursor protein (APP). To determine whether increased cholinergic neurotransmission can modify the APP processing in vi...

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Main Authors: Lin, L., Georgievska, B., Mattsson, A., Isacson, O.
Formáid: Artigo
Teanga:Inglês
Foilsithe: The National Academy of Sciences 1999
Ábhair:
Biological Sciences
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC18420/
https://ncbi.nlm.nih.gov/pubmed/10518584
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