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Suppression or induction of apoptosis by opposing pathways downstream from calcium-activated calcineurin

Ca(2+)-mobilizing compounds such as the Ca(2+) ionophore A23187 or the endoplasmic reticulum Ca(2+) ATPase inhibitor thapsigargin can suppress or induce apoptosis in the same cells. The use of different calcineurin inhibitors has shown that both suppression and induction of apoptosis by the Ca(2+)-m...

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Autori principali: Lotem, Joseph, Kama, Rachel, Sachs, Leo
Natura: Artigo
Lingua:Inglês
Pubblicazione: The National Academy of Sciences 1999
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC18404/
https://ncbi.nlm.nih.gov/pubmed/10518568
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