Effects of DksA, GreA, and GreB on transcription initiation: insights into the mechanisms of factors that bind in the secondary channel of RNA polymerase

Escherichia coli DksA, GreA, and GreB have similar structures and bind to the same location on RNA polymerase (RNAP), the secondary channel. We show that GreB can fulfill some roles of DksA in vitro, including shifting the promoter-open complex equilibrium in the dissociation direction, thus allowin...

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Détails bibliographiques
Auteurs principaux: Rutherford, Steven T., Lemke, Justin J., Vrentas, Catherine E., Gaal, Tamas, Ross, Wilma, Gourse, Richard L.
Format: Artigo
Langue:Inglês
Publié: 2006
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1839928/
https://ncbi.nlm.nih.gov/pubmed/17207814
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2006.12.013
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