Spontaneous and antigen-induced production of HIV-inhibitory β-chemokines are associated with AIDS-free status

The β-chemokines RANTES, macrophage inflammatory protein (MIP)-1α, and MIP-1β suppress infection by macrophage-tropic strains of HIV and simian immunodeficiency virus (SIV) by binding and down-regulating the viral coreceptor, CCR5. Accordingly, we have examined whether higher levels of CCR5 ligands...

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Bibliographic Details
Main Authors: Garzino-Demo, Alfredo, Moss, Ronald B., Margolick, Joseph B., Cleghorn, Farley, Sill, Anne, Blattner, William A., Cocchi, Fiorenza, Carlo, Dennis J., DeVico, Anthony L., Gallo, Robert C.
Format: Artigo
Language:Inglês
Published: The National Academy of Sciences 1999
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC18399/
https://ncbi.nlm.nih.gov/pubmed/10518563
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