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5-ASA Affects Cell Cycle Progression in Colorectal Cells by Reversibly Activating a Replication Checkpoint

BACKGROUND & AIMS: Individuals with inflammatory bowel disease are at risk of developing colorectal cancer (CRC). Epidemiologic, animal, and laboratory studies suggest that 5-amino-salicylic acid (5-ASA) protects from the development of CRC by altering cell cycle progression and by inducing apop...

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Detalhes bibliográficos
Main Authors: LUCIANI, M. GLORIA, CAMPREGHER, CHRISTOPH, FORTUNE, JOHN M., KUNKEL, THOMAS A., GASCHE, CHRISTOPH
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1839818/
https://ncbi.nlm.nih.gov/pubmed/17241873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2006.10.016
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