Gem Associates with Ezrin and Acts via the Rho-GAP Protein Gmip to Down-Regulate the Rho Pathway

Gem is a protein of the Ras superfamily that plays a role in regulating voltage-gated Ca(2+) channels and cytoskeletal reorganization. We now report that GTP-bound Gem interacts with the membrane–cytoskeleton linker protein Ezrin in its active state, and that Gem binds to active Ezrin in cells. The...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Hatzoglou, Anastassia, Ader, Isabelle, Splingard, Anne, Flanders, James, Saade, Evelyne, Leroy, Ingrid, Traver, Sabine, Aresta, Sandra, de Gunzburg, Jean
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: The American Society for Cell Biology 2007
Pynciau:
Articles
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC1839077/
https://ncbi.nlm.nih.gov/pubmed/17267693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E06-06-0510
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