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HEPARIN MODULATES THE 99-LOOP OF FACTOR IXa: EFFECTS ON REACTIVITY WITH ISOLATED KUNITZ-TYPE INHIBITOR DOMAINS

Reactivity of factor IXa with basic pancreatic trypsin inhibitor is enhanced by low molecular weight heparin (enoxaparin). Previous studies by us have suggested that this effect involves allosteric modulation of factor IXa. We examined the reactivity of factor IXa with several isolated Kunitz-type i...

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Detalhes bibliográficos
Principais autores: Neuenschwander, Pierre F., Williamson, Stephen R., Nalian, Armen, Baker-Deadmond, Kimberly J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1839010/
https://ncbi.nlm.nih.gov/pubmed/16766524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M603743200
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