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Competition for antigen determines the stability of T cell–dendritic cell interactions during clonal expansion

The regulation of T cell–dendritic cell (DC) contacts during clonal expansion is poorly defined. Although optimal CD4 T cell responses require prolonged exposure to antigen (Ag), it is believed that stable T cell–DC interactions occur only during the first day of the activation process. Here we show...

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Autors principals: Garcia, Zacarias, Pradelli, Emmanuelle, Celli, Susanna, Beuneu, Hélène, Simon, Aurélie, Bousso, Philippe
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2007
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1838639/
https://ncbi.nlm.nih.gov/pubmed/17360562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0610019104
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