uPAR and HER-2 gene status in individual breast cancer cells from blood and tissues

Overexpression of urokinase plasminogen activator system or HER-2 (erbB-2) in breast cancer is associated with a poor prognosis. HER-2 overexpression is caused by HER-2 gene amplification. The anti-HER-2 antibody trastuzumab significantly improves clinical outcome for HER2-positive breast cancer. Dr...

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Hlavní autoři: Meng, Songdong, Tripathy, Debu, Shete, Sanjay, Ashfaq, Raheela, Saboorian, Hossein, Haley, Barbara, Frenkel, Eugene, Euhus, David, Leitch, Marilyn, Osborne, Cynthia, Clifford, Edward, Perkins, Steve, Beitsch, Peter, Khan, Amanullah, Morrison, Larry, Herlyn, Dorothee, Terstappen, Leon W. M. M., Lane, Nancy, Wang, Jianqiang, Uhr, Jonathan
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2006
Témata:
Biological Sciences
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1838539/
https://ncbi.nlm.nih.gov/pubmed/17079488
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0608113103
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