A novel mitochondrial matrix serine/threonine protein phosphatase regulates the mitochondria permeability transition pore and is essential for cellular survival and development

Mitochondria play a central role in the regulation of programmed cell death signaling. Here, we report the finding of a mitochondrial matrix-targeted protein phosphatase 2C family member (PP2Cm) that regulates mitochondrial membrane permeability transition pore (MPTP) opening and is essential for ce...

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Detalhes bibliográficos
Main Authors: Lu, Gang, Ren, Shuxun, Korge, Paavo, Choi, Jayoung, Dong, Yuan, Weiss, James, Koehler, Carla, Chen, Jau-nian, Wang, Yibin
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2007
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1838530/
https://ncbi.nlm.nih.gov/pubmed/17374715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1499107
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