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Characterization of mutations and loss of heterozygosity of p53 and K-ras2 in pancreatic cancer cell lines by immobilized polymerase chain reaction

BACKGROUND: The identification of known mutations in a cell population is important for clinical applications and basic cancer research. In this work an immobilized form of the polymerase chain reaction, referred to as polony technology, was used to detect mutations as well as gene deletions, result...

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Autors principals: Butz, James, Wickstrom, Eric, Edwards, Jeremy
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2003
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC183853/
https://ncbi.nlm.nih.gov/pubmed/12877750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6750-3-11
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