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Diagnosis of pancreatic adenocarcinoma by polymerase chain reaction from pancreatic secretions.

As mutations at codon 12 of the Ki-ras oncogene have been shown to occur in 90% of pancreatic adenocarcinomas, a novel strategy for the detection of these mutations in pancreatic secretions obtained at routine endoscopies was developed. Ki-ras DNA was amplified and screened for the presence of mutat...

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Autors principals: Trümper, L. H., Bürger, B., von Bonin, F., Hintze, A., von Blohn, G., Pfreundschuh, M., Daus, H.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 1994
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2033495/
https://ncbi.nlm.nih.gov/pubmed/8054276
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