Haplotype Association between Haptoglobin (Hp2) and Hp Promoter SNP (A-61C) May Explain Previous Controversy of Haptoglobin and Malaria Protection

BACKGROUND: Malaria is one of the strongest recent selective pressures on the human genome, as evidenced by the high levels of varying haemoglobinopathies in human populations–despite the increased risk of mortality in the homozygous states. Previously, functional polymorphisms of Hp, coded by the c...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Cox, Sharon E., Doherty, Conor, Atkinson, Sarah H., Nweneka, Chidi V., Fulford, Anthony J.C., Ghattas, Hala, Rockett, Kirk A., Kwiatkowski, Dominic P., Prentice, Andrew M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2007
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1838521/
https://ncbi.nlm.nih.gov/pubmed/17426810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0000362
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados