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Sensitivity of T cells to antigen and antagonism emerges from differential regulation of the same molecular signaling module
Activation of T helper cells is necessary for the adaptive immune response to pathogens, and spurious activation can result in organ-specific autoimmunity (e.g., multiple sclerosis). T cell activation is initiated by membrane-proximal signaling that is predicated on the binding of the T cell recepto...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1838481/ https://ncbi.nlm.nih.gov/pubmed/17360359 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0611482104 |
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