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Crystal structure of the carbapenemase OXA-24 reveals insights into the mechanism of carbapenem hydrolysis

Combating bacterial resistance to β-lactams, the most widely used antibiotics, is an emergent and clinically important challenge. OXA-24 is a class D β-lactamase isolated from a multiresistant epidemic clinical strain of Acinetobacter baumannii. We have investigated how OXA-24 specifically hydrolyze...

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Detalhes bibliográficos
Main Authors: Santillana, Elena, Beceiro, Alejandro, Bou, Germán, Romero, Antonio
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1838445/
https://ncbi.nlm.nih.gov/pubmed/17374723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0607557104
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