Activity of 2-(3,4-dichlorophenoxy)-5-nitrobenzonitrile (MDL-860) against picornaviruses in vitro.

The newly synthesized compound 2-(3,4-dichlorophenoxy)-5-nitrobenzonitrile (MDL-860) has been found to inhibit picornavirus replication. In multiple growth cycle experiments, 1 microgram of MDL-860 per ml caused a reduction in virus yield of at least 1.0 log10 50% tissue culture infectious doses per...

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Pubblicato in:	Antimicrob Agents Chemother
Autori principali:	Powers, R D, Gwaltney, J M, Hayden, F G
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1982
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC183806/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7181475/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.22.4.639
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