Interaction of azthreonam and related monobactams with beta-lactamases from gram-negative bacteria.
Monobactams containing 3 beta-aminothiazolyl oxime side chains (SQ 81,377, SQ 81,402, azthreonam, and SQ 26,917) have poor affinities for the broad-spectrum beta-lactamases TEM-2 and K1. Addition of a 4-methyl substituent significantly increased stability to hydrolysis by these enzymes. P99 cephalos...
שמור ב:
| הוצא לאור ב: | Antimicrob Agents Chemother |
|---|---|
| Principais autores: | , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
American Society for Microbiology (ASM)
1982
|
| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC183759/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6982680/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.22.3.414 |
| תגים: |
אין תגיות, היה/י הראשונ/ה לתייג את הרשומה!
|