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Regulation of nuclear translocation of Forkhead transcription factor AFX by protein kinase B

The regulation of intracellular localization of AFX, a human Forkhead transcription factor, was studied. AFX was recovered as a phosphoprotein from transfected COS-7 cells growing in the presence of FBS, and the phosphorylation was eliminated by wortmannin, a potent inhibitor of phosphatidylinositol...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Takaishi, Hiroshi, Konishi, Hiroaki, Matsuzaki, Hidenori, Ono, Yoshitaka, Shirai, Yasuhito, Saito, Naoaki, Kitamura, Tadahiro, Ogawa, Wataru, Kasuga, Masato, Kikkawa, Ushio, Nishizuka, Yasutomi
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1999
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC18373/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10518537/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.21.11836
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