d-Serine is an endogenous ligand for the glycine site of the N-methyl-d-aspartate receptor

Functional activity of N-methyl-d-aspartate (NMDA) receptors requires both glutamate binding and the binding of an endogenous coagonist that has been presumed to be glycine, although d-serine is a more potent agonist. Localizations of d-serine and it biosynthetic enzyme serine racemase approximate t...

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Главные авторы: Mothet, Jean-Pierre, Parent, Angèle T., Wolosker, Herman, Brady, Roscoe O., Linden, David J., Ferris, Christopher D., Rogawski, Michael A., Snyder, Solomon H.
Формат: Artigo
Язык:Inglês
Опубликовано: The National Academy of Sciences 2000
Предметы:
Biological Sciences
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC18334/
https://ncbi.nlm.nih.gov/pubmed/10781100
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