Nalaganje...
Correction of prototypic ATM splicing mutations and aberrant ATM function with antisense morpholino oligonucleotides
We used antisense morpholino oligonucleotides (AMOs) to redirect and restore normal splicing of three prototypic splicing mutations in the ataxia-telangiectasia mutated (ATM) gene. Two of the mutations activated cryptic 5′ or 3′ splice sites within exonic regions; the third mutation activated a down...
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| Main Authors: | , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
National Academy of Sciences
2007
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1832221/ https://ncbi.nlm.nih.gov/pubmed/17389389 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0608616104 |
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