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INSULIN-LIKE GROWTH FACTOR (IGF)-I AMELIORATES DEMYELINATION INDUCED BY TUMOR NECROSIS FACTOR (TNF)-α IN TRANSGENIC MICE
Our laboratories have reported that TNF-α causes myelin damage and apoptosis of oligodendrocytes and their precursors in vitro and in vivo. We also have reported that IGF-I can protect cultured oligodendrocytes and their precursors from TNF-α-induced damage. In this study, we investigated whether IG...
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2007
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1832145/ https://ncbi.nlm.nih.gov/pubmed/17279553 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jnr.21181 |
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