15-Deoxy-Δ(12,14)-prostaglandin J(2) inhibits multiple steps in the NF-κB signaling pathway

Prostaglandin J(2) (PGJ(2)) and its metabolites Δ(12)-PGJ(2) and 15-deoxy-Δ(12,14)-PGJ(2) (15d-PGJ(2)) are naturally occurring derivatives of prostaglandin D(2) that have been suggested to exert antiinflammatory effects in vivo. 15d-PGJ(2) is a high-affinity ligand for the peroxisome proliferator-ac...

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Detalles Bibliográficos
Main Authors: Straus, Daniel S., Pascual, Gabriel, Li, Mei, Welch, John S., Ricote, Mercedes, Hsiang, Chin-Hui, Sengchanthalangsy, Lei Lei, Ghosh, Gourisankar, Glass, Christopher K.
Formato: Artigo
Idioma:Inglês
Publicado: The National Academy of Sciences 2000
Assuntos:
Biological Sciences
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC18320/
https://ncbi.nlm.nih.gov/pubmed/10781090
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