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Rab27b regulates number and secretion of platelet dense granules

The Rab27 GTPase subfamily consists of two closely related homologs, Rab27a and Rab27b. Rab27a has been shown previously to regulate organelle movement and regulated exocytosis in a wide variety of secretory cells. However, the role of the more restrictedly expressed Rab27b remains unclear. Here we...

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Détails bibliographiques
Auteurs principaux: Tolmachova, Tanya, Åbrink, Magnus, Futter, Clare E., Authi, Kalwant S., Seabra, Miguel C.
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2007
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1831675/
https://ncbi.nlm.nih.gov/pubmed/17384153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0609879104
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