Nidogen 1 and 2 gene promoters are aberrantly methylated in human gastrointestinal cancer

BACKGROUND: Nidogens are highly conserved proteins of basement membranes. Two nidogen proteins, nidogen 1 and nidogen 2, are known in mammals. RESULTS: We show that CpG islands of both NID1 and NID2 genes are aberrantly methylated in human cancer samples and cancer cell lines. For both genes, methyl...

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Detalhes bibliográficos
Main Authors: Ulazzi, Linda, Sabbioni, Silvia, Miotto, Elena, Veronese, Angelo, Angusti, Angela, Gafà, Roberta, Manfredini, Stefano, Farinati, Fabio, Sasaki, Takako, Lanza, Giovanni, Negrini, Massimo
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2007
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1831485/
https://ncbi.nlm.nih.gov/pubmed/17328794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-6-17
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