Φορτώνει......
Positive and Negative Design in Stability and Thermal Adaptation of Natural Proteins
The aim of this work is to elucidate how physical principles of protein design are reflected in natural sequences that evolved in response to the thermal conditions of the environment. Using an exactly solvable lattice model, we design sequences with selected thermal properties. Compositional analys...
Αποθηκεύτηκε σε:
| Κύριοι συγγραφείς: | , , |
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| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
Public Library of Science
2007
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1829478/ https://ncbi.nlm.nih.gov/pubmed/17381236 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.0030052 |
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