Accumulation of Mutant Neuroserpin Precedes Development of Clinical Symptoms in Familial Encephalopathy with Neuroserpin Inclusion Bodies

Intracellular protein deposition due to aggregation caused by conformational alteration is the hallmark of a number of neurodegenerative disorders, including Parkinson’s disease, tauopathies, Huntington’s disease, and familial encephalopathy with neuroserpin inclusion bodies. The latter is an autoso...

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Detalhes bibliográficos
Main Authors: Galliciotti, Giovanna, Glatzel, Markus, Kinter, Jochen, Kozlov, Serguei V., Cinelli, Paolo, Rülicke, Thomas, Sonderegger, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2007
Assuntos:
Regular Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1829463/
https://ncbi.nlm.nih.gov/pubmed/17392169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2007.060910
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