Therapeutic Targeting of CC Ligand 21 or CC Chemokine Receptor 7 Abrogates Pulmonary Fibrosis Induced by the Adoptive Transfer of Human Pulmonary Fibroblasts to Immunodeficient Mice

Idiopathic interstitial pneumonias (IIPs) are a collection of pulmonary fibrotic diseases of unknown etiopathogenesis. CC chemokine receptor 7 (CCR7) is expressed in IIP biopsies and primary fibroblast lines, but its role in pulmonary fibrosis was not previously examined. To study the in vivo role o...

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Hlavní autoři: Pierce, Elizabeth M., Carpenter, Kristin, Jakubzick, Claudia, Kunkel, Steven L., Flaherty, Kevin R., Martinez, Fernando J., Hogaboam, Cory M.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Investigative Pathology 2007
Témata:
Regular Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1829450/
https://ncbi.nlm.nih.gov/pubmed/17392156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2007.060649
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